David Feldman Selected Research

1,25-dihydroxyvitamin D

1/2014	Vitamin D receptor mutations in patients with hereditary 1,25-dihydroxyvitamin D-resistant rickets.
11/2012	Combination of calcitriol and dietary soy exhibits enhanced anticancer activity and increased hypercalcemic toxicity in a mouse xenograft model of prostate cancer.
6/2012	Dietary vitamin D₃ and 1,25-dihydroxyvitamin D₃ (calcitriol) exhibit equivalent anticancer activity in mouse xenograft models of breast and prostate cancer.
12/2011	The role of vitamin D receptor mutations in the development of alopecia.
11/2011	Hereditary vitamin D-resistant rickets (HVDRR) owing to a heterozygous mutation in the vitamin D receptor.
8/2010	Two new unrelated cases of hereditary 1,25-dihydroxyvitamin D-resistant rickets with alopecia resulting from the same novel nonsense mutation in the vitamin D receptor gene.
1/2010	Hereditary 1,25-dihydroxyvitamin D-resistant rickets with alopecia resulting from a novel missense mutation in the DNA-binding domain of the vitamin D receptor.
10/2009	Hereditary vitamin D resistant rickets: identification of a novel splice site mutation in the vitamin D receptor gene and successful treatment with oral calcium therapy.
4/2009	Compound heterozygous mutations in the vitamin D receptor in a patient with hereditary 1,25-dihydroxyvitamin D-resistant rickets with alopecia.
4/2007	A unique insertion/duplication in the VDR gene that truncates the VDR causing hereditary 1,25-dihydroxyvitamin D-resistant rickets without alopecia.

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David Feldman Research Topics

Disease

41	Prostatic Neoplasms (Prostate Cancer) 01/2016 - 05/2002
35	Neoplasms (Cancer) 11/2020 - 05/2002
17	Rickets (Rachitis) 12/2020 - 11/2002
16	Breast Neoplasms (Breast Cancer) 01/2020 - 07/2003
14	Familial Hypophosphatemic Rickets (X-Linked Hypophosphatemia) 01/2014 - 11/2002
11	Neoplasm Metastasis (Metastasis) 11/2020 - 01/2003
10	Alopecia (Baldness) 01/2013 - 11/2002
9	Heart Failure 12/2017 - 07/2008
8	Vitamin D Deficiency 12/2020 - 10/2002
8	Hypocalcemia 01/2014 - 11/2002
8	Inborn Genetic Diseases (Disease, Hereditary) 02/2012 - 11/2002
5	Insulin Resistance 01/2018 - 05/2012
5	Inflammation (Inflammations) 01/2018 - 04/2006
5	Hypertension (High Blood Pressure) 01/2018 - 06/2009
4	Disease Progression 01/2016 - 01/2009
4	Secondary Hyperparathyroidism 01/2014 - 11/2002
3	Scoliosis 10/2018 - 01/2010
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2018 - 02/2015
3	Pain (Aches) 01/2018 - 08/2005
3	Hypophosphatemia 01/2014 - 04/2009
2	Osteoporosis 01/2019 - 01/2010
2	Melanoma (Melanoma, Malignant) 07/2018 - 08/2011
2	Obesity 04/2016 - 05/2012
2	Essential Hypertension 02/2015 - 12/2006
2	Cushing Syndrome 04/2014 - 09/2012
2	Hypercalcemia (Milk Alkali Syndrome) 07/2013 - 11/2012
2	Glycogen Storage Disease Type VI (Glycogenosis Type VI) 09/2012 - 08/2009
2	Hypophosphatemic Rickets 06/2010 - 01/2010
2	Carcinogenesis 01/2009 - 03/2007
1	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 05/2022
1	Thinness 01/2022
1	Ulcerative Colitis 01/2022
1	Hypercholesterolemia 01/2022
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2022
1	Dyslipidemias (Dyslipidemia) 01/2022
1	Psoriasis (Pustulosis Palmaris et Plantaris) 12/2020
1	Metabolic Bone Diseases (Osteopenia) 12/2020
1	Anemia 09/2020
1	Wounds and Injuries (Trauma) 02/2020

Drug/Important Bio-Agent (IBA)

47	Vitamin D FDA LinkGeneric 12/2020 - 10/2002
36	Calcitriol (Calcijex)FDA LinkGeneric 04/2016 - 10/2002
25	Calcitriol Receptors (Calcitriol Receptor)IBA 12/2020 - 11/2002
19	1,25-dihydroxyvitamin DIBA 01/2014 - 11/2002
10	AndrogensIBA 01/2016 - 05/2002
9	25-hydroxyvitamin DIBA 01/2020 - 08/2011
8	hydroxide ionIBA 01/2020 - 06/2004
8	Estrogen ReceptorsIBA 01/2020 - 01/2010
8	CalciumIBA 08/2015 - 05/2004
6	Estrogens (Estrogen)FDA Link 01/2018 - 01/2010
6	Androgen Receptors (Androgen Receptor)IBA 01/2016 - 05/2002
6	ProstaglandinsIBA 05/2009 - 09/2005
5	Aromatase (CYP19)IBA 04/2016 - 12/2009
5	Hormones (Hormone)IBA 07/2013 - 06/2006
5	LigandsIBA 04/2012 - 05/2002
5	EnzymesIBA 01/2011 - 01/2003
5	Prostate-Specific Antigen (Semenogelase)IBA 11/2008 - 01/2003
4	Proteins (Proteins, Gene)FDA Link 04/2012 - 06/2004
4	GenisteinIBA 05/2009 - 09/2005
3	Pharmaceutical PreparationsIBA 01/2018 - 03/2007
3	Biological ProductsIBA 01/2018 - 08/2009
3	Glucose (Dextrose)FDA LinkGeneric 04/2015 - 04/2014
3	Cholecalciferol (Vitamin D3)FDA Link 07/2013 - 02/2009
3	Alkaline PhosphataseIBA 01/2013 - 11/2002
3	Messenger RNA (mRNA)IBA 06/2012 - 06/2004
3	DNA (Deoxyribonucleic Acid)IBA 04/2012 - 01/2010
3	Insulin-Like Growth Factor Binding Protein 3IBA 08/2009 - 10/2006
3	Insulin-Like PeptidesIBA 02/2008 - 07/2003
3	Complementary DNA (cDNA)IBA 05/2004 - 01/2003
2	oxidized low density lipoproteinIBA 05/2022 - 01/2022
2	LDL CholesterolIBA 01/2022 - 01/2022
2	Biomarkers (Surrogate Marker)IBA 01/2018 - 09/2012
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2018 - 09/2005
2	Dinoprostone (PGE2)FDA Link 04/2016 - 09/2005
2	GlucocorticoidsIBA 01/2016 - 05/2002
2	Insulin (Novolin)FDA Link 04/2015 - 02/2015
2	Mifepristone (RU 486)FDA Link 04/2014 - 09/2012
2	VitaminsIBA 07/2013 - 06/2012
2	25-Hydroxyvitamin D3 1-alpha-Hydroxylase (25 Hydroxyvitamin D3 1 alpha Hydroxylase)IBA 07/2013 - 06/2012
2	Ketoconazole (Nizoral)FDA LinkGeneric 09/2012 - 10/2002
2	Nonsense Codon (Nonsense Mutation)IBA 08/2010 - 12/2002
2	Co-Repressor ProteinsIBA 11/2009 - 08/2007
2	Naproxen (Naprosyn)FDA LinkGeneric 09/2009 - 01/2009
2	IsoflavonesIBA 05/2009 - 05/2009
2	Anti-Mullerian HormoneIBA 04/2009 - 03/2007
2	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 03/2009 - 07/2008
2	CaspasesIBA 02/2009 - 07/2003
2	Selenious Acid (Selenite)IBA 11/2008 - 08/2006
2	SeleniumIBA 11/2008 - 08/2006
2	Triamcinolone (Aristocort)FDA Link 05/2006 - 05/2002
1	CarbohydratesIBA 01/2022

Therapy/Procedure

25	Therapeutics 11/2020 - 10/2002
4	Heart-Assist Devices 12/2017 - 06/2009
3	Chemoprevention 01/2011 - 01/2003
2	Length of Stay 10/2018 - 01/2014
2	Transplantation 08/2014 - 12/2009
2	Prostatectomy (Retropubic Prostatectomy) 05/2009 - 01/2003
1	Ketogenic Diet 01/2022
1	Cell Transplantation 01/2022
1	Carbohydrate-Restricted Diet (Low Carbohydrate Diet) 01/2022
1	Knee Replacement Arthroplasty (Total Knee Replacement) 09/2020